The Belgian, who won bronze in the individual time-trial at last year’s UCI Road World Championships in Innsbruck, Austria, will hope to beat the 54.526km benchmark that has eluded his contemporaries in recent times.
The 27-year-old Lotto-Soudal rider has chosen the Velodromo Bicentenario in Aguascalientes, Mexico, for his attempt and trained in Namibia for several weeks to simulate the conditions that are expected.
The most recent rider to fail in his bid to dethrone Wiggins is Mikkel Bjerg, who covered 53.730km in Odense, Denmark, on October 4 last year. The Dane is planning another attempt in September.
Others to come close were Tom Zirbel (53.037km), Martin Toft Madsen (53.630km) and Dion Beukeboom (52.757).
Micah Gross (48.255km) and Marc Dubois (48.337) fell well short of the mark.
Apart from his ride at the Worlds, Campenaerts also claimed individual time-trial golds at the European and national championships in 2018 and most recently won the final-day time-trial at Tirreno-Adriatico in March.